Remedy on the Expression Stage and Methylation Standing of Genes

MiR-340 promotes the proliferation of vascular easy muscle cells by focusing on von Hippel-Lindau tumor suppressor (VHL) gene

MiRNAs play key roles within the proliferation of vascular easy muscle cells (VSMCs). Nonetheless, the roles and underlying mechanism of miRNAs in VSMCs aren’t totally understood. The goal of this examine was to guage the position of miR-340 within the proliferation of VSMCs.

The expression ranges of miR-340 and von Hippel-Lindau tumor-suppressor (VHL) in VSMCs induced by platelet-derived progress issue (PDGF) -BB or fetal bovine serum (FBS) had been measured by q-PCR. The consequences of miR-340 and VHL on cell proliferation and invasion had been evaluated by CCK-Eight assay.

  • Goal gene prediction and screening in addition to luciferase reporter assay had been carried out to confirm the downstream goal genes of miR-340. Western blotting was used to detect the protein expression ranges of vascular endothelial progress issue (VEGF) and VHL.
  • Our outcomes confirmed that the miR-340 was up-regulated in PDGF-BB_ENREF_1or FBS induced VSMCs. As well as, overexpression of miR-340 promoted VSMCs proliferation and invasion. Furthermore, VHL was discovered to be a possible goal for miR-340, and up-regulation of VHL inhibited VSMCs proliferation.
  • MiR-340 performs a important position in VSMC proliferation and neointimal hyperplasia in rats carotid balloon harm mannequin. Diminished expression ranges of miR-340 promoted VHL-inhibited VSMCs proliferation.
  • In conclusion, miR-340 might play a job within the regulation of proliferation of VSMCs by inhibition of VHL.

The Affiliation between Periodontitis and Human Colorectal Most cancers: Genetic and Pathogenic Linkage

Periodontitis has been associated to an elevated risk of and mortality associated to human colorectal most cancers (CRC). Current proof attributes such an affiliation to the direct and indirect outcomes of virulence elements belonging to periodontal pathogens, to inflammatory mediators and to genetic elements.

The targets of the analysis have been to guage the existence of a genetic linkage between periodontitis and human CRC, to ascertain genes thought-about predominant in such a linkage, thus named chief genes, and to search out out pathogenic mechanisms related to the merchandise of chief genes.

Genes linking periodontitis and CRC have been acknowledged and labeled in order of predominance, by an experimental investigation, carried out by means of laptop computer simulation, utilizing the chief gene methodology.

Pathogenic mechanisms concerning chief genes have been determined by cross-search databases. Of the 83 genes linking periodontitis and CRC, 12 have been labeled as chief genes and have been pathogenically implicated in cell cycle regulation and inside the immune-inflammatory response. The current outcomes, obtained by means of laptop computer simulation and requiring further validation, help the existence of a genetic linkage between periodontitis and CRC. Cell cycle dysregulation and the alteration of the immuno-inflammatory response signify the pathogenic mechanisms related to the merchandise of chief genes.

rhodococcus
rhodococcus

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), APC-Cy7

4-CAC060Hu22-APC-Cy7
  • EUR 715.20
  • EUR 8148.00
  • EUR 2154.00
  • EUR 955.20
  • EUR 394.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with APC-Cy7.

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), Biotinylated

4-CAC060Hu22-Biotin
  • EUR 384.00
  • EUR 3110.40
  • EUR 912.00
  • EUR 472.80
  • EUR 267.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with Biotin.

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), Cy3

4-CAC060Hu22-Cy3
  • EUR 522.00
  • EUR 5478.00
  • EUR 1482.00
  • EUR 682.80
  • EUR 309.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with Cy3.

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), FITC

4-CAC060Hu22-FITC
  • EUR 367.20
  • EUR 3340.80
  • EUR 943.20
  • EUR 463.20
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with FITC.

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), HRP

4-CAC060Hu22-HRP
  • EUR 392.40
  • EUR 3613.20
  • EUR 1015.20
  • EUR 495.60
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with HRP.

Platelet Derived Growth Factor Receptor Alpha (PDGFRa) Monoclonal Antibody (Human), PE

4-CAC060Hu22-PE
  • EUR 367.20
  • EUR 3340.80
  • EUR 943.20
  • EUR 463.20
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Platelet Derived Growth Factor Receptor Alpha (PDGFRa). This antibody is labeled with PE.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig)

4-CAF548Hu01
  • EUR 280.80
  • EUR 2774.40
  • EUR 696.00
  • EUR 350.40
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1)

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), APC

4-CAF548Hu01-APC
  • EUR 391.20
  • EUR 3606.00
  • EUR 1014.00
  • EUR 495.60
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with APC.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), APC-Cy7

4-CAF548Hu01-APC-Cy7
  • EUR 639.60
  • EUR 7068.00
  • EUR 1884.00
  • EUR 847.20
  • EUR 362.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with APC-Cy7.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), Biotinylated

4-CAF548Hu01-Biotin
  • EUR 356.40
  • EUR 2714.40
  • EUR 813.60
  • EUR 433.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with Biotin.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), Cy3

4-CAF548Hu01-Cy3
  • EUR 471.60
  • EUR 4758.00
  • EUR 1302.00
  • EUR 610.80
  • EUR 288.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with Cy3.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), FITC

4-CAF548Hu01-FITC
  • EUR 337.20
  • EUR 2908.80
  • EUR 835.20
  • EUR 420.00
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with FITC.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), HRP

4-CAF548Hu01-HRP
  • EUR 358.80
  • EUR 3145.20
  • EUR 898.80
  • EUR 448.80
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with HRP.

Lamin B1 (LMNB1) Polyclonal Antibody (Human, Pig), PE

4-CAF548Hu01-PE
  • EUR 337.20
  • EUR 2908.80
  • EUR 835.20
  • EUR 420.00
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Pig Lamin B1 (LMNB1). This antibody is labeled with PE.

Lamin B1 (LMNB1) Monoclonal Antibody (Human)

4-CAF548Hu22
  • EUR 290.40
  • EUR 2932.80
  • EUR 732.00
  • EUR 364.80
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1)

Lamin B1 (LMNB1) Monoclonal Antibody (Human), APC

4-CAF548Hu22-APC
  • EUR 406.80
  • EUR 3822.00
  • EUR 1068.00
  • EUR 517.20
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with APC.

Lamin B1 (LMNB1) Monoclonal Antibody (Human), APC-Cy7

4-CAF548Hu22-APC-Cy7
  • EUR 669.60
  • EUR 7500.00
  • EUR 1992.00
  • EUR 890.40
  • EUR 375.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with APC-Cy7.

Lamin B1 (LMNB1) Monoclonal Antibody (Human), Biotinylated

4-CAF548Hu22-Biotin
  • EUR 368.40
  • EUR 2872.80
  • EUR 853.20
  • EUR 448.80
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with Biotin.

Lamin B1 (LMNB1) Monoclonal Antibody (Human), Cy3

4-CAF548Hu22-Cy3
  • EUR 492.00
  • EUR 5046.00
  • EUR 1374.00
  • EUR 639.60
  • EUR 296.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with Cy3.

Lamin B1 (LMNB1) Monoclonal Antibody (Human), FITC

4-CAF548Hu22-FITC
  • EUR 349.20
  • EUR 3081.60
  • EUR 878.40
  • EUR 436.80
  • EUR 231.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with FITC.

Lamin B1 (LMNB1) Monoclonal Antibody (Human), HRP

4-CAF548Hu22-HRP
  • EUR 372.00
  • EUR 3332.40
  • EUR 945.60
  • EUR 468.00
  • EUR 244.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with HRP.

Lamin B1 (LMNB1) Monoclonal Antibody (Human), PE

4-CAF548Hu22-PE
  • EUR 349.20
  • EUR 3081.60
  • EUR 878.40
  • EUR 436.80
  • EUR 231.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin B1 (LMNB1). This antibody is labeled with PE.

Lamin A/C (LMNA) Polyclonal Antibody (Human)

4-CAF550Hu01
  • EUR 285.60
  • EUR 2853.60
  • EUR 714.00
  • EUR 357.60
  • EUR 252.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA)

Lamin A/C (LMNA) Polyclonal Antibody (Human), APC

4-CAF550Hu01-APC
  • EUR 398.40
  • EUR 3714.00
  • EUR 1040.40
  • EUR 506.40
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC.

Lamin A/C (LMNA) Polyclonal Antibody (Human), APC-Cy7

4-CAF550Hu01-APC-Cy7
  • EUR 654.00
  • EUR 7284.00
  • EUR 1938.00
  • EUR 868.80
  • EUR 369.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC-Cy7.

Lamin A/C (LMNA) Polyclonal Antibody (Human), Biotinylated

4-CAF550Hu01-Biotin
  • EUR 362.40
  • EUR 2793.60
  • EUR 832.80
  • EUR 440.40
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Biotin.

Lamin A/C (LMNA) Polyclonal Antibody (Human), Cy3

4-CAF550Hu01-Cy3
  • EUR 482.40
  • EUR 4902.00
  • EUR 1338.00
  • EUR 625.20
  • EUR 291.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Cy3.

Lamin A/C (LMNA) Polyclonal Antibody (Human), FITC

4-CAF550Hu01-FITC
  • EUR 343.20
  • EUR 2995.20
  • EUR 856.80
  • EUR 428.40
  • EUR 229.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with FITC.

Lamin A/C (LMNA) Polyclonal Antibody (Human), HRP

4-CAF550Hu01-HRP
  • EUR 366.00
  • EUR 3238.80
  • EUR 921.60
  • EUR 458.40
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with HRP.

Lamin A/C (LMNA) Polyclonal Antibody (Human), PE

4-CAF550Hu01-PE
  • EUR 343.20
  • EUR 2995.20
  • EUR 856.80
  • EUR 428.40
  • EUR 229.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with PE.

Lamin A/C (LMNA) Monoclonal Antibody (Human)

4-CAF550Hu22
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA)

Lamin A/C (LMNA) Monoclonal Antibody (Human), APC

4-CAF550Hu22-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC.

Lamin A/C (LMNA) Monoclonal Antibody (Human), APC-Cy7

4-CAF550Hu22-APC-Cy7
  • EUR 699.60
  • EUR 7932.00
  • EUR 2100.00
  • EUR 933.60
  • EUR 388.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with APC-Cy7.

Lamin A/C (LMNA) Monoclonal Antibody (Human), Biotinylated

4-CAF550Hu22-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Biotin.

Lamin A/C (LMNA) Monoclonal Antibody (Human), Cy3

4-CAF550Hu22-Cy3
  • EUR 512.40
  • EUR 5334.00
  • EUR 1446.00
  • EUR 668.40
  • EUR 304.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with Cy3.

Lamin A/C (LMNA) Monoclonal Antibody (Human), FITC

4-CAF550Hu22-FITC
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with FITC.

Lamin A/C (LMNA) Monoclonal Antibody (Human), HRP

4-CAF550Hu22-HRP
  • EUR 385.20
  • EUR 3519.60
  • EUR 992.40
  • EUR 486.00
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with HRP.

Lamin A/C (LMNA) Monoclonal Antibody (Human), PE

4-CAF550Hu22-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Lamin A/C (LMNA). This antibody is labeled with PE.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human)

4-CAG369Hu01
  • EUR 280.80
  • EUR 2774.40
  • EUR 696.00
  • EUR 350.40
  • EUR 249.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1)

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), APC

4-CAG369Hu01-APC
  • EUR 391.20
  • EUR 3606.00
  • EUR 1014.00
  • EUR 495.60
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), APC-Cy7

4-CAG369Hu01-APC-Cy7
  • EUR 639.60
  • EUR 7068.00
  • EUR 1884.00
  • EUR 847.20
  • EUR 362.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC-Cy7.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), Biotinylated

4-CAG369Hu01-Biotin
  • EUR 356.40
  • EUR 2714.40
  • EUR 813.60
  • EUR 433.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Biotin.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), Cy3

4-CAG369Hu01-Cy3
  • EUR 471.60
  • EUR 4758.00
  • EUR 1302.00
  • EUR 610.80
  • EUR 288.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Cy3.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), FITC

4-CAG369Hu01-FITC
  • EUR 337.20
  • EUR 2908.80
  • EUR 835.20
  • EUR 420.00
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with FITC.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), HRP

4-CAG369Hu01-HRP
  • EUR 358.80
  • EUR 3145.20
  • EUR 898.80
  • EUR 448.80
  • EUR 238.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with HRP.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody (Human), PE

4-CAG369Hu01-PE
  • EUR 337.20
  • EUR 2908.80
  • EUR 835.20
  • EUR 420.00
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with PE.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human)

4-CAG369Hu22
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1)

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), APC

4-CAG369Hu22-APC
  • EUR 436.80
  • EUR 4254.00
  • EUR 1176.00
  • EUR 560.40
  • EUR 272.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), APC-Cy7

4-CAG369Hu22-APC-Cy7
  • EUR 729.60
  • EUR 8364.00
  • EUR 2208.00
  • EUR 976.80
  • EUR 402.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with APC-Cy7.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), Biotinylated

4-CAG369Hu22-Biotin
  • EUR 390.00
  • EUR 3189.60
  • EUR 932.40
  • EUR 480.00
  • EUR 270.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Biotin.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), Cy3

4-CAG369Hu22-Cy3
  • EUR 532.80
  • EUR 5622.00
  • EUR 1518.00
  • EUR 697.20
  • EUR 313.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with Cy3.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), FITC

4-CAG369Hu22-FITC
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with FITC.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), HRP

4-CAG369Hu22-HRP
  • EUR 398.40
  • EUR 3706.80
  • EUR 1039.20
  • EUR 505.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with HRP.

ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Monoclonal Antibody (Human), PE

4-CAG369Hu22-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human ATPase, Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1). This antibody is labeled with PE.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human)

4-CAG901Hu01
  • EUR 289.20
  • EUR 2900.40
  • EUR 724.80
  • EUR 361.20
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1)

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), APC

4-CAG901Hu01-APC
  • EUR 403.20
  • EUR 3778.80
  • EUR 1057.20
  • EUR 512.40
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), APC-Cy7

4-CAG901Hu01-APC-Cy7
  • EUR 663.60
  • EUR 7413.60
  • EUR 1970.40
  • EUR 880.80
  • EUR 373.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC-Cy7.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), Biotinylated

4-CAG901Hu01-Biotin
  • EUR 366.00
  • EUR 2840.40
  • EUR 844.80
  • EUR 445.20
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Biotin.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), Cy3

4-CAG901Hu01-Cy3
  • EUR 488.40
  • EUR 4988.40
  • EUR 1359.60
  • EUR 633.60
  • EUR 295.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Cy3.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), FITC

4-CAG901Hu01-FITC
  • EUR 346.80
  • EUR 3046.80
  • EUR 868.80
  • EUR 433.20
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with FITC.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), HRP

4-CAG901Hu01-HRP
  • EUR 369.60
  • EUR 3294.00
  • EUR 936.00
  • EUR 464.40
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with HRP.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Polyclonal Antibody (Human), PE

4-CAG901Hu01-PE
  • EUR 346.80
  • EUR 3046.80
  • EUR 868.80
  • EUR 433.20
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with PE.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human)

4-CAG901Hu22
  • EUR 310.80
  • EUR 3249.60
  • EUR 804.00
  • EUR 393.60
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1)

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), APC

4-CAG901Hu22-APC
  • EUR 436.80
  • EUR 4254.00
  • EUR 1176.00
  • EUR 560.40
  • EUR 272.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), APC-Cy7

4-CAG901Hu22-APC-Cy7
  • EUR 729.60
  • EUR 8364.00
  • EUR 2208.00
  • EUR 976.80
  • EUR 402.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with APC-Cy7.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), Biotinylated

4-CAG901Hu22-Biotin
  • EUR 390.00
  • EUR 3189.60
  • EUR 932.40
  • EUR 480.00
  • EUR 270.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Biotin.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), Cy3

4-CAG901Hu22-Cy3
  • EUR 532.80
  • EUR 5622.00
  • EUR 1518.00
  • EUR 697.20
  • EUR 313.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with Cy3.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), FITC

4-CAG901Hu22-FITC
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with FITC.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), HRP

4-CAG901Hu22-HRP
  • EUR 398.40
  • EUR 3706.80
  • EUR 1039.20
  • EUR 505.20
  • EUR 255.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with HRP.

Voltage Dependent Anion Channel Protein 1 (VDAC1) Monoclonal Antibody (Human), PE

4-CAG901Hu22-PE
  • EUR 373.20
  • EUR 3427.20
  • EUR 964.80
  • EUR 471.60
  • EUR 242.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Mouse monoclonal antibody against Human Voltage Dependent Anion Channel Protein 1 (VDAC1). This antibody is labeled with PE.

Human Angiotensin II (AngII) CLIA Kit

4-CCA005Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Angiotensin II (AngII)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Human Glycated Hemoglobin A1c (HbA1c) CLIA Kit

4-CCA190Hu
  • EUR 6178.80
  • EUR 3324.00
  • EUR 819.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Glycated Hemoglobin A1c (HbA1c)serum, plasma and erythrocyte lysates

Human Anti-Mullerian Hormone (AMH) CLIA Kit

4-CCA228Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Anti-Mullerian Hormone (AMH)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

General Bovine Serum Albumin (BSA) CLIA Kit

4-CCA248Ge
  • EUR 6649.20
  • EUR 3573.60
  • EUR 874.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Bovine Serum Albumin (BSA)Serum, plasma and other biological fluids

Cattle Substance P (SP) CLIA Kit

4-CCA393Bo
  • EUR 8157.60
  • EUR 4371.60
  • EUR 1052.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Cattle Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Dog Substance P (SP) CLIA Kit

4-CCA393Ca
  • EUR 7780.80
  • EUR 4172.40
  • EUR 1008.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Dog Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Guinea pig Substance P (SP) CLIA Kit

4-CCA393Gu
  • EUR 7780.80
  • EUR 4172.40
  • EUR 1008.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Guinea pig Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Human Substance P (SP) CLIA Kit

4-CCA393Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Substance P (SP) CLIA Kit

4-CCA393Mu
  • EUR 7026.00
  • EUR 3772.80
  • EUR 919.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Mouse Substance P (SP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Rat Substance P (SP) CLIA Kit

4-CCA393Ra
  • EUR 7404.00
  • EUR 3973.20
  • EUR 963.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat Substance P (SP)serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

General Dehydroepiandrosterone (DHEA) CLIA Kit

4-CCA398Ge
  • EUR 6649.20
  • EUR 3573.60
  • EUR 874.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Dehydroepiandrosterone (DHEA)serum, plasma and other biological fluids

ELISA Kit for Luteinizing Hormone (LH)

4-CCA441Mu
  • EUR 6351.60
  • EUR 3355.20
  • EUR 840.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Luteinizing Hormone (LH) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Luteinizing Hormone (LH) CLIA Kit

4-CCA441Ra
  • EUR 6210.00
  • EUR 3340.80
  • EUR 823.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat Luteinizing Hormone (LH)serum, plasma and other biological fluids

Human C-Peptide (CP) CLIA Kit

4-CCA447Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human C-Peptide (CP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Rat C-Peptide (CP) CLIA Kit

4-CCA447Ra
  • EUR 7404.00
  • EUR 3973.20
  • EUR 963.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat C-Peptide (CP)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

Human Insulin (INS) CLIA Kit

4-CCA448Hu
  • EUR 6837.60
  • EUR 3673.20
  • EUR 896.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Human Insulin (INS)Serum, plasma, cell culture supernates and other biological fluids

Rat Insulin (INS) CLIA Kit

4-CCA448Ra
  • EUR 7404.00
  • EUR 3973.20
  • EUR 963.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of Rat Insulin (INS)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids

General Thyroxine (T4) CLIA Kit

4-CCA452Ge
  • EUR 6649.20
  • EUR 3573.60
  • EUR 874.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Thyroxine (T4)Serum, plasma and other biological fluids

General Triiodothyronine (T3) CLIA Kit

4-CCA453Ge
  • EUR 6649.20
  • EUR 3573.60
  • EUR 874.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Triiodothyronine (T3)Serum, plasma and other biological fluids

General Estriol (E3) CLIA Kit

4-CCA455Ge
  • EUR 6649.20
  • EUR 3573.60
  • EUR 874.80
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Competitive Inhibition chemiluminescent immunoassay for detection of General Estriol (E3)Serum, plasma and other biological fluids

The Have an effect on of Energy Delicate Stress and Agomelatine Treatment on the Expression Stage and Methylation Standing of Genes Involved in Tryptophan Catabolic Pathway in PBMCs and Thoughts Constructions

Despair is the extraordinary psychological dysfunction. Earlier analysis counsel that the occasion mechanism of melancholy may be associated to issues of the tryptophan catabolic pathway (TRYCAT). Thus, this analysis investigates the impression of agomelatine remedy on the expression and methylation standing of genes involved in TRYCAT inside the thoughts and blood of rats uncovered to a persistent delicate stress (CMS).

Separate groups of rats have been uncovered to CMS for two or seven weeks; the second group acquired automotive or agomelatine for five weeks. After completion of every stress conditions and remedy, the expression ranges of messenger RNA (mRNA) and protein, along with the methylation standing of promoters, have been measured in peripheral blood mononuclear cells (PBMCs) and in thoughts constructions with utilizing TaqMan Gene Expression Assay,

Western blot, and methylation-sensitive high-resolution melting methods. In PBMCs, Kmo mRNA expression elevated inside the group after CMS, whereas this impression was normalized by agomelatine treatment. In thoughts, KatI and KatII expression modified following CMS publicity.

Moreover, CMS decreased the methylation standing of the second Tdo2 promoter inside the amygdala. Protein expression of Tph1, Tph2, Ido1, and KatII modified inside the group after CMS and agomelatine administration, most prominently inside the basal ganglia, cerebral cortex, hippocampus, and amygdala.

The outcomes level out that CMS and agomelatine affect the mRNA and protein expression, along with the methylation of promoters of genes involved inside the tryptophan catabolic pathway.

Place of Air Air air pollution and rs10830963 Polymorphism on the Incidence of Sort 2 Diabetes: Tehran Cardiometabolic Genetic Analysis

Diabetes mellitus (DM) is taken under consideration one in every of many fundamental effectively being factors that are egregiously threatening human life all by the world. Quite a lot of epidemiological analysis have examined the connection of a selected matter < 10 μm (PM10) publicity and with form 2 diabetes mellitus (T2DM) prevalence and incidence.

Accordingly, the current analysis is a analysis investigating the neutral have an effect on of air air air pollution (AP) and rs10830963 on the incidence of T2DM. An entire number of 2428 adults over 20 years of age participated in a possible cohort (TCGS) all through a 9-year follow-up part.

The main target of AP was measured, and the obtained values have been thought-about the suggest diploma in three earlier years given that publicity focus took the oldsters dwelling in that location.

The COX regression model was employed to search out out the have an effect on of AP and rs10830963 on the incidence of T2DM in adjustment with covariate elements. Among the many many 392 T2DM, 230 circumstances (58.7%) have been female diabetics, and 162 (41.3%) have been male diabetics.

In line with the multivariable-adjusted model, publicity to PM10 (per 10 μm/m3), associated to the hazard of T2DM, although solely a borderline (p = 0.07) was found inside the multivariable model (HR; 1.50, 95% CI; 1-2.32).

The rs10830963 was straight associated to the incidence of diabetes, and the GG genotype elevated the T2DM cost by 113% (higher than two situations) (HR; 2.134, 95% CI; 1.42-3.21, p ≤ 0.001) and GC elevated it by 65% (HR; 1.65, 95% CI; 1.24-2.21, p ≤ 0.001).

Prolonged-term publicity to PM10 was associated with an elevated risk of diabetes. Thus, it is urged that the individuals with variant rs10830963 genotypes fall inside a bunch susceptible to an elevated risk of T2DM arising from AP.

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